Prostate Cancer Patients on Aspirin Therapy More Likely to Die, Study Says: "Prostate Cancer, hormone treatments and aspirin therapy could be a deadly combination. According to research published in the December 27th issue of the New England Journal of Medicine, men undergoing hormone therapy for prostate cancer—and who take baby aspirin to protect their heart—run a significantly higher risk of dying. Apparently, baby aspirin side effects interact with the hormone therapy, elevating liver-function test levels. Liver function testing is a routine part of cancer-fighting treatments. Because of this, the man must stop potentially lifesaving hormone therapy. Hormonal therapy involves reducing levels of male hormones called androgens and is a common treatment for prostate cancer. Because this type of therapy can raise the risk of a heart attack, men who are older or have known coronary risk factors such as diabetes or smoking, generally include baby aspirin in their treatment protocol while undergoing hormone therapy because aspirin helps prevent blood clots."